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aaltaai on "good info for repeat miscarriers"

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hello,

i just wanted to add my two cents. i am a repeat mc'er, with 8 losses under my belt. most have been between 5-8 weeks, but have also had 2 later losses, of a singlteton at 10 wks and identical twins at 11 wks. i had done every standard prelimnary test out there: chromosomal (on me, dh, and various d&c tissue), hsg, mthfr, etc., etc. all they could find was that i was mthfr compound hetero, which should not have caused the issue. however, i was put on 40mg of lovenox and daily baby asiprin, which did little, as 5 losses were post that.

i finally went into a rheumotologist while actively mc'ing and did a full blood work up. interestingly, this work up looked different than the ones when i was not pg or still in the healthy throes of pg. it showed more advanced clotting and a "markedly high" autoimmune response of no known scientfic qunatity. for my next ivf i upped to 80mg of lovenox, and also added low dose prednisone (steroids), the latter beginning 2 weeks before the ivf. the latter is often associated with natrual killer cells, which many us scientists believe is total bunk. however, with 8 losses under my belt, the rhumotologist deferred to me whether i started the steroids. there are risks, but i am now 11wks pg with a baby that seems on track.

i also just received a ton of literature on celiacs/gluten intolerance that is just coming out. they are discovering that a much larger % of the pop has the disease, but it is asymptomatic, so therefore not diagnosed. it has been highly linked to infertility, repeat miscarriage, and iugr babies. it is also linked to mthfr, pcos, and autoimmune repsonses. i am not the one to jump on medical bandwagons, but it is quite compelling. a doc at columbia is sort of leading the charge, but prelimnary studies all over the world are being done in regards to asymptomatic celiacs. i have just gone gluten free and will stay so for the remainder of the pg.

so, my two cents are, if you are unknown, those are two potential avenues to examine -- autoimmune/natural killer cells and celiacs. good luck.


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